Article

The DNA binding protein BCL6 regulates NFκB-controlled endothelial inflammatory gene expression

2022-11-04

Abstract excerpt

<h4>Background</h4> NFκB drives acute vascular inflammation by activating gene expression programs in endothelial cells to promote leukocyte recruitment. Numerous negative feedback regulators of NFκB activation have been defined that promote resolution of inflammation. However, the identities of endogenous suppressors of NFκB transcription are less clear. In macrophages, the transcriptional repressor BCL6 was sho...

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Literature Corpus work: fcc4dbbe-dfcd-5610-aaa6-4cc5b2743e6f
DOI: 10.1101/2022.11.03.514942

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