Article

The fitness cost and benefit of phase separated protein deposits

2019-03-12

Abstract excerpt

<h4>ABSTRACT</h4> Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane-less compartments for many cellular processes. What are the fitness costs and benefits of forming such deposits in different conditions? Using a model protein that phase separates into deposits, we distinguish and quantify the fitness contribu...

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Literature Corpus work: 70e13ab4-be9a-5b93-ae41-442d5ac7b8d7
DOI: 10.1101/574657

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