Article

Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells

2021-02-22

Abstract excerpt

Genetic differences are a primary reason for differences in the susceptibility and severity of coronavirus disease 2019 (COVID-19). Because induced pluripotent stem (iPS) cells maintain the genetic information of the donor, they can be used to model individual differences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vitro . Notably, undifferentiated human iPS cells themselves canno...

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Literature Corpus work: 70d7a744-dd27-55f0-b4b1-5e3794f333fb
DOI: 10.1101/2021.02.22.432218

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