Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders

11 Sept 2020

Abstract excerpt

It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS) disorders. However, little is known about the mechanism that triggers the COVID-19-associated CNS disorders, due to the lack of appropriate experimental systems. Our present study showed that angiotensin-converting enzyme-2 (ACE2), a cellular receptor for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Connective Tissue Growth Factor Research
Share to Long-Term Effects of COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32934757
DOI: 10.1186/s41232-020-00143-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disordersPMID 32934757Read ↗

Poor sensitivity of iPSC-derived neural progenitors and glutamatergic neurons to SARS-CoV-2Semantic proximity Read ↗

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic MechanismsSemantic proximity Read ↗

Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral OrganoidsSemantic proximity Read ↗

Innate immune response to SARS-CoV-2 infection contributes to neuronal damage in human iPSC-derived peripheral neuronsSemantic proximity Read ↗

Analysis of ACE2 Genetic Variability among Populations Highlights a Possible Link with COVID-19-Related Neurological Complications.Semantic proximity Read ↗

ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk FactorsSemantic proximity Read ↗

SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepitheliumSemantic proximity Read ↗

Sex-biased response to and brain cell infection by SARS-CoV-2 in a highly susceptible human ACE2 transgenic modelSemantic proximity Read ↗

ACE2 interaction networks in COVID-19: a physiological framework for prediction of outcome in patients with cardiovascular risk factorsSemantic proximity Read ↗

SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes accumulation of HIF1ɑ and phosphorylated tauSemantic proximity Read ↗

SARS-CoV-2 infects neurons, astrocytes, choroid plexus epithelial cells and pericytes of the human central nervous systemSemantic proximity Read ↗

Analysis of ACE2 Genetic Variability Among Populations Highlights A Possible Link With COVID19-Related Neurological ComplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.