Article

Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in Zebrafish Heart

2023-07-10

Abstract excerpt

<h4>Background: </h4> Long QT syndrome (LQTS) can lead to ventricular arrhythmia and sudden cardiac death. The most common congenital cause of LQTS is mutations in the channel subunits generating the cardiac potassium current IKs. Zebrafish (Danio rerio) have been proposed as a powerful system to model human cardiac diseases due to the similar electrical properties of the zebrafish heart and the human heart. <h4>M...

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Literature Corpus work: 70cb68dd-4e9c-59fa-b637-49cacc812a4c
DOI: 10.20944/preprints202307.0603.v1

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