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Article

α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish

5 Feb 2020

Abstract excerpt

α-asarone is a natural phenylpropene found in several plants, which are widely used for flavoring foods and treating diseases. Previous studies have demonstrated that α-asarone has many pharmacological functions, while some reports indicated its toxicity. However, little is known about its cardiovascular effects. This study investigated developmental toxicity of α-asarone in zebrafish, especially the...

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PMID: 32035120
DOI: 10.1016/j.toxlet.2020.02.003

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