Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart

1 Jan 2012

Abstract excerpt

BACKGROUND: Cardiovascular toxicity is a major limiting factor in drug development and requires multiple cost-effective models to perform toxicological evaluation. Zebrafish is an excellent model for many developmental, toxicological and regenerative studies. Using approaches like morpholino knockdown and electrocardiogram, researchers have demonstrated physiological and functional similarities between zebrafish...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Congenital heart defects research
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22449203
DOI: 10.1186/1472-6793-12-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heartPMID 22449203Read ↗

Functional Genomics in Zebrafish as a Tool to Identify Novel Antiarrhythmic TargetsSemantic proximity Read ↗

Using Zebrafish for High-Throughput Screening of Novel Cardiovascular DrugsSemantic proximity Read ↗

Automated high-throughput heart rate measurement in medaka and zebrafish embryos under physiological conditionsSemantic proximity Read ↗

Adult and Developing Zebrafish as Suitable Models for Cardiac Electrophysiology and Pathology in Research and IndustrySemantic proximity Read ↗

A Novel Art of Electrocardiogram Assessment in Zebrafish for Cardiovascular Disease Studies and Drug ScreeningSemantic proximity Read ↗

Utility of Zebrafish Models of Acquired and Inherited Long QT SyndromeSemantic proximity Read ↗

Advances in the Study of Heart Development and Disease Using ZebrafishSemantic proximity Read ↗

The zebrafish as a tool to identify novel therapies for human cardiovascular diseaseSemantic proximity Read ↗

Zebrafish Model Reveals Early Electrocardiographic and Molecular Signatures of Doxorubicin-Induced Cardiotoxicity.Semantic proximity Read ↗

A Doxorubicin-induced Cardiomyopathy Model in Adult ZebrafishSemantic proximity Read ↗

A guide to analysis of cardiac phenotypes in the zebrafish embryo.Semantic proximity Read ↗

High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.