Article
Phages produce persisters.
Microbial biotechnology - 1 Aug 2024
Fernández-García Laura, Kirigo Joy, Huelgas-Méndez Daniel, Benedik Michael J, Tomás María, García-Contreras Rodolfo, Wood Thomas K
Abstract excerpt
Arguably, the greatest threat to bacteria is phages. It is often assumed that those bacteria that escape phage infection have mutated or utilized phage-defence systems; however, another possibility is that a subpopulation forms the dormant persister state in a manner similar to that demonstrated for bacterial cells undergoing nutritive, oxidative, and antibiotic stress. Persister cells do not undergo mutation and...
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