Article

Decoding Treatment Choice: Genetic and Phenotypic Analyses of Long-term Antidepressant Acceptability

2025-08-21

Abstract excerpt

<h4>Importance</h4> Antidepressant treatment remains largely trial-and-error, with approximately one-third of patients with major depressive disorder (MDD) reporting inefficacy of first-line medications. Identifying predictors of treatment acceptability is needed to improve prescribing precision and patient outcomes. <h4>Objective</h4> To identify phenotypic and genetic signatures associated with antidepressant...

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Literature Corpus work: 70c1c8ea-c64f-5555-a6ac-a82d43a5dadc
DOI: 10.1101/2025.08.19.25333784

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