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Article

Hijacking a neurodevelopmental epigenomic program in metastatic dissemination of medulloblastoma

2022-01-24

Abstract excerpt

<title>Abstract</title> <p>How dysregulation of neurodevelopment relates to medulloblastoma (MB), the most common pediatric brain tumor, remains elusive. Here, we uncovered a neurodevelopmental epigenomic program being hijacked to induce MB metastatic dissemination. Unsupervised analyses by integrating publicly available datasets with our newly generated data revealed that SMARCD3/BAF60C regulates DAB1-mediated R...

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Identifiers and source

Literature Corpus work
70240bdc-a318-5575-bad3-1ddcd5922cf8
DOI
10.21203/rs.3.rs-1270726/v1
Open publication

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Hijacking a neurodevelopmental epigenomic program in metastatic dissemination of medulloblastomaDOI 10.21203/rs.3.rs-1270726/v1
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