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Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry

14 Jun 2024

Abstract excerpt

ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order. LCMV is associated with fatal disease in immunocompromised populations and, as the prototypical arenavirus member, acts as a model for the many highly pathogenic members of the Arenaviridae family, such as Junín, Lassa, and Lujo viruses, all...

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PMID: 38874413
DOI: 10.1128/mbio.01684-23

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