Article

The virus-encoded ion channel “viroporin” activity of the agnoprotein is required for BK Polyomavirus release from infected kidney cells

2023-01-30

Abstract excerpt

BK polyomavirus (BKPyV) is a common opportunistic pathogen and the causative agent of several diseases in transplant patients and the immunosuppressed. Despite its importance, aspects of the virus lifecycle such as how the virus exits an infected cells, remain poorly understood. The late region of the BKPyV genome encodes an auxillery protein called agnoprotein. We and others have shown that agnoprotein is an esse...

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Literature Corpus work: f1ac3cb4-dcaa-5160-b426-e10ed41a7d5d
DOI: 10.1101/2023.01.30.526200

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