Article

MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis

2024-10-22

Abstract excerpt

<h4>ABSTRACT</h4> High-dose radiation exposure results in gastrointestinal (GI) acute radiation syndrome identified by the destruction of mucosal layer, intestinal epithelial barrier dysfunction, and aberrant inflammatory responses. In addition, radiation causes gut microbiome dysbiosis characterized by diminished microbial diversity, reduction in the abundance of beneficial commensal bacteria, and the spread of...

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Literature Corpus work: d5fef722-b1a9-5948-8965-3fdfa26e3085
DOI: 10.1101/2024.10.22.619652

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