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Crypt-top and crypt-bottom colonic epithelial cell population microRNA expression demonstrates cell type-specificity and correlation with endoscopic activity in ulcerative colitis

2022-09-26

Abstract excerpt

<h4>Background and Aims</h4> Colonic epithelial barrier loss and dysfunction are one of the early events in ulcerative colitis (UC) and microRNAs (miRNAs) participate in its regulation. However, cell type-specific profile of miRNAs during inflammation in UC is still unknown. Thus, we aimed to perform miRNA profiling on colon tissue and epithelial cell levels in active and quiescent UC. <h4>Methods</h4> Small RNA-s...

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Literature Corpus work
6fc9f8f7-c39f-55dc-9288-e10a85d38f09
DOI
10.1101/2022.09.25.22280336
Open publication

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Crypt-top and crypt-bottom colonic epithelial cell population microRNA expression demonstrates cell type-specificity and correlation with endoscopic activity in ulcerative colitisDOI 10.1101/2022.09.25.22280336
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