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Article

MicroRNAs Expression in the Ileal Pouch of Patients with Ulcerative Colitis Is Robustly Up-Regulated and Correlates with Disease Phenotypes.

PloS one - 1 Jan 2016

Ben-Shachar Shay, Yanai Henit, Sherman Horev Hadas, Elad Hofit, Baram Liran, Issakov Ofer, Tulchinsky Hagit, Pasmanik-Chor Metsada, Shomron Noam, Dotan Iris

Abstract excerpt

BACKGROUND: Gene expression alterations are associated with disease behavior in inflammatory bowel disease (IBD). microRNAs (miRNAs) are dominant in the regulation of gene expression, and may affect IBD phenotype. Our aim was to assess mucosal miRNA expression in IBD and the correlation with intestinal inflammation. METHODS: We performed a large-scale analysis of ileal mucosal miRNA. Biopsies were retrieved from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27536783
DOI: 10.1371/journal.pone.0159956
PMCID: PMC4990209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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