Back to search

Article

Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanics Patients Treated with Clopidogrel: Abundance and Functionality

2024-08-30

Abstract excerpt

Clopidogrel; a prescription drug to reduce ischemic events in cardiovascular patients; has been extensively studied in mostly European individuals but not among Caribbean Hispanics. This study evaluated the low abundance and reduced activity of paraoxonase-1 (PON1) in clopidogrel-resistant patients as a predictive risk biomarker of poor responders and disease severity in this population. Thirty-six patients on clo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6fbc624a-f21e-54f0-9c23-c7df7470946c
DOI
10.20944/preprints202401.0514.v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanics Patients Treated with Clopidogrel: Abundance and FunctionalityDOI 10.20944/preprints202401.0514.v2
Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanic Patients Treated with Clopidogrel: Abundance and Functionality.Semantic proximity
Paraoxonase-1 is a major determinant of clopidogrel efficacy.Semantic proximity
Unveiling the mysteries of clopidogrel metabolism and efficacy.Semantic proximity
Implementing a Pharmacogenomic-driven Algorithm to Guide Antiplatelet Therapy among Caribbean Hispanics: A non-randomized prospective cohort studySemantic proximity
Relationship between paraoxonase-1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study.Semantic proximity
Influence of high-density lipoprotein and paraoxonase-1 on platelet reactivity in patients with acute coronary syndromes receiving clopidogrel therapy.Semantic proximity
The diversity and clinical implications of genetic variants influencing clopidogrel bioactivation and response in the Emirati population.Semantic proximity
Pharmacogenomic polygenic risk score for clopidogrel responsiveness among Caribbean Hispanics: A candidate gene approach.Semantic proximity
Pharmacogenomics of clopidogrel: evidence and perspectives.Semantic proximity
Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.Semantic proximity
Association between Paraoxonase-1 p.Q192R Polymorphism and Coronary Artery Disease susceptibility in the Colombian Population.Semantic proximity
Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction.Semantic proximity
Select a neighboring publication to make it the new centre.