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Article

Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanic Patients Treated with Clopidogrel: Abundance and Functionality.

International journal of molecular sciences - 3 Oct 2024

Monero-Paredes Mariangeli, Santiago Ednalise, Carrasquillo-Carrion Kelvin, Renta Jessicca Y, Rogozin Igor B, Roche-Lima Abiel, Duconge Jorge

Abstract excerpt

Clopidogrel, a prescription drug to reduce ischemic events in cardiovascular patients, has been extensively studied in mostly European individuals but not among Caribbean Hispanics. This study evaluated the low abundance and reduced activity of paraoxonase-1 (PON1) in clopidogrel-resistant patients as a predictive risk biomarker of poor responders and disease severity in this population. Thirty-six patients on...

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Identifiers

PMID: 39408985
DOI: 10.3390/ijms251910657
PMCID: PMC11477108

Genes

PON1

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Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanic Patients Treated with Clopidogrel: Abundance and Functionality.PMID 39408985Read ↗

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