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Virulence determinant, PTP7, controls vesicle budding from the Maurer’s clefts, adhesin protein trafficking and host cell remodeling in <i>Plasmodium falciparum</i>

2021-08-12

Abstract excerpt

Presentation of the variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (EMP1), at knob-like protrusions on the surface of infected red blood cells, underpins P. falciparum malaria pathogenicity. Here we describe a protein PF3D7_0301700 (PTP7), that functions at the nexus between the intermediate trafficking organelle, the Maurer’s cleft, and the infected red blood cell surface. Genetic disrupt...

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Literature Corpus work
6fb4c3f5-913a-5952-9c72-aa791a40f894
DOI
10.1101/2021.08.12.456062
Open publication

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Virulence determinant, PTP7, controls vesicle budding from the Maurer’s clefts, adhesin protein trafficking and host cell remodeling in <i>Plasmodium falciparum</i>DOI 10.1101/2021.08.12.456062
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