Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking.

Molecular microbiology - 1 Dec 2015

McHugh Emma, Batinovic Steven, Hanssen Eric, McMillan Paul J, Kenny Shannon, Griffin Michael D W, Crawford Simon, Trenholme Katharine R, Gardiner Donald L, Dixon Matthew W A, Tilley Leann

Abstract excerpt

The malaria parasite Plasmodium falciparum dramatically remodels its host red blood cell to enhance its own survival, using a secretory membrane system that it establishes outside its own cell. Cisternal organelles, called Maurer's clefts, act as a staging point for the forward trafficking of virulence proteins to the red blood cell (RBC) membrane. The Ring-EXported Protein-1 (REX1) is a Maurer's cleft resident...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD36 Antigens
Share to DNA, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythrocyte Membrane

Share to Erythrocytes

Share to Gene Knockdown Techniques

Share to Plasmodium falciparum

Share to Protozoan Proteins

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26304012
DOI: 10.1111/mmi.13201
PMCID: PMC4987487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking.PMID 26304012Read ↗

Genetic ablation of a Maurer's cleft protein prevents assembly of the Plasmodium falciparum virulence complexSemantic proximity Read ↗

Targeted mutagenesis of the ring‐exported protein‐1 of <i>Plasmodium falciparum</i> disrupts the architecture of Maurer's cleft organellesSemantic proximity Read ↗

Role of Plasmodium falciparum Protein GEXP07 in Maurer’s Cleft Morphology, Knob Architecture, and P. falciparum EMP1 TraffickingSemantic proximity Read ↗

An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytesSemantic proximity Read ↗

Maurer's clefts, the enigma of <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human ErythrocytesSemantic proximity Read ↗

Sequence requirements for the export of the <i>Plasmodium falciparum</i> Maurer's clefts protein REX2Semantic proximity Read ↗

MAHRP2, an exported protein of Plasmodium falciparum, is an essential component of Maurer's cleft tethersSemantic proximity Read ↗

A Plasmodium homolog of ER tubule‐forming proteins is required for parasite virulenceSemantic proximity Read ↗

Virulence determinant, PTP7, controls vesicle budding from the Maurer’s clefts, adhesin protein trafficking and host cell remodeling in <i>Plasmodium falciparum</i>Semantic proximity Read ↗

The Exported Protein PbCP1 Localises to Cleft-Like Structures in the Rodent Malaria Parasite Plasmodium bergheiSemantic proximity Read ↗

Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.