Article
Targeted mutagenesis of the ring‐exported protein‐1 of <i>Plasmodium falciparum</i> disrupts the architecture of Maurer's cleft organelles
20 Jun 2008
Abstract excerpt
Mature red blood cells have no internal trafficking machinery, so the intraerythrocytic malaria parasite, Plasmodium falciparum, establishes its own transport system to export virulence factors to the red blood cell surface. Maurer's clefts are parasite-derived membranous structures that form an important component of this exported secretory system. A protein with sequence similarity to a Golgi tethering protein,...
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