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Article

DNA methylation reprogramming during oogenesis and interference by reproductive technologies: Studies in mouse and bovine models

15 May 2015

Abstract excerpt

The use of assisted reproductive technology (ART) to overcome fertility problems has continued to increase since the birth of the first baby conceived by ART over 30 years ago. Similarly, embryo transfer is widely used as a mechanism to advance genetic gain in livestock. Despite repeated optimisation of ART treatments, pre- and postnatal outcomes remain compromised. Epigenetic mechanisms play a fundamental role...

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PMID: 25976160
DOI: 10.1071/rd14333

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