Article

NINJ1 promotes lung adenocarcinoma progression via activation of the PI3K-AKT signaling axis and suppression of cell death pathways

2025-07-21

Abstract excerpt

<title>Abstract</title> <p>Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, and current therapeutic options often fail to yield sustained responses. Ninjurin1 (NINJ1), a transmembrane protein implicated in plasma membrane rupture during lytic cell death, has recently emerged as a potential antitumor target, yet its role in LUAD pathogenesis remains poorly defined. Here, we comprehen...

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Literature Corpus work: 6f4e1dfb-a445-5f8b-859e-5ffcbe1df2e9
DOI: 10.21203/rs.3.rs-6906860/v1

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