Article

NINJ1 mediates hepatic ischemia-reperfusion injury

2026-02-10

Abstract excerpt

Hepatic ischemia-reperfusion injury (IRI) results from interrupted perfusion to the liver and contributes to acute liver dysfunction such as following liver transplantation. Lytic cell death pathways are major drivers of IRI and the subsequent inflammatory response. The transmembrane protein ninjurin-1 (NINJ1) was identified as the key executor of terminal plasma membrane rupture across multiple lytic cell death p...

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Literature Corpus work: 1736d037-6f0b-5bc3-8c5b-c66630eb5ab7
DOI: 10.64898/2026.02.07.704585

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