Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy

22 Apr 2024

Abstract excerpt

Non-small-cell lung cancer (NSCLC), a common malignant tumor, requires deeper pathogenesis investigation. Autophagy is an evolutionarily conserved lysosomal degradation process that is frequently blocked during cancer progression. It is an urgent need to determine the novel autophagy-associated regulators in NSCLC. Here, we found that pirin was upregulated in NSCLC, and its expression was positively correlated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Polyamine Metabolism and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38648079
DOI: 10.1021/acs.jproteome.3c00871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress AutophagyPMID 38648079Read ↗

UCHL1 promotes lung cancer progression by stabilizing YAP1 and reprogramming ceramide metabolismSemantic proximity Read ↗

Josephin domain containing 2 (JOSD2) promotes lung cancer by inhibiting LKB1 (Liver kinase B1) activitySemantic proximity Read ↗

Regulation of autophagy flux by E3 ubiquitin ligase Pirh2 in lung cancerSemantic proximity Read ↗

NINJ1 promotes lung adenocarcinoma progression via activation of the PI3K-AKT signaling axis and suppression of cell death pathwaysSemantic proximity Read ↗

PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathwaySemantic proximity Read ↗

Inhibition of DKC1  Induces Telomere-related Senescence and Apoptosis in Lung Adenocarcinoma Semantic proximity Read ↗

Cezanne promoted autophagy through PIK3C3 stabilization and PIK3C2A transcription in lung adenocarcinomaSemantic proximity Read ↗

The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectivesSemantic proximity Read ↗

Regulatory effect of LncRNA DRAIC/miR-149-5p/NFIB molecular network on autophagy of esophageal cancer cells and its biological behaviorSemantic proximity Read ↗

DEPDC1 up‐regulates RAS expression to inhibit autophagy in lung adenocarcinoma cellsSemantic proximity Read ↗

Inhibition of DKC1 induces telomere-related senescence and apoptosis in lung adenocarcinomaSemantic proximity Read ↗

CLDN1 Increases Drug Resistance of Non-Small Cell Lung Cancer by Activating Autophagy via Up-Regulation of ULK1 PhosphorylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.