Article

Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms

2024-11-01

Abstract excerpt

Chronic pain affects 20-30% of the population and imposes a significant socio-economic burden as it is often accompanied by substantial emotional comorbidities such as anxiety and depression. Yet, the mechanisms underlying the interactions between the sensory and emotional aspects of chronic pain remain poorly understood. Here, we investigated the role of FKBP51, a regulator of the stress response, in mediating bo...

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Literature Corpus work: 6f2aae96-da1a-59e5-838d-cc87d9da00be
DOI: 10.1101/2024.11.01.621278

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