Article

Brief, repeated isoflurane anaesthesia elicits sex-dependent behavioural, cerebrovascular, and microglial alterations in mice

2026-02-12

Abstract excerpt

General anaesthetics are indispensable tools in biomedical research, yet growing evidence shows that their effects on brain function extend beyond the transient loss of consciousness for which they are used. Although numerous preclinical studies have examined the impact of a single anaesthetic exposure, far less is known about the cumulative consequences of repeated administration protocols, despite their widespre...

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Literature Corpus work: 6f142125-18de-5582-9bfd-c84583ac46b7
DOI: 10.64898/2026.02.11.705306

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