Article

fuNTRp: Identifying protein positions for variation driven functional tuning

2019-03-16

Abstract excerpt

<h4>ABSTRACT</h4> Evaluating the impact of non-synonymous genetic variants is essential for uncovering disease associations and mechanisms of evolution. Understanding corresponding sequence changes is also fundamental for synthetic protein design and stability assessments. However, the performance gain of variant effect predictors observed in recent years is not in line with the increased complexity of new method...

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Literature Corpus work: 6efe14c6-8049-589b-ac49-be33bc36cc3a
DOI: 10.1101/578757

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