Article

Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

2019-02-28

Abstract excerpt

Although genome-wide association studies (GWAS) have a dramatic impact on susceptibility locus discovery, this univariate approach has limitation in detecting complex genotype-phenotype correlations. It is essential to identify shared genetic risk factors acting through common biological mechanisms of autoimmune diseases with a multivariate analysis. In this study, the GWAS summary statistics including 41,274 sing...

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Literature Corpus work: 6efb4463-9303-553e-8369-3473a639244d
DOI: 10.1101/563973

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