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BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against <i>Chlamydia</i>

2023-11-05

Abstract excerpt

The protein basic helix-loop-helix family member e40 (BHLHE40) is a transcription factor recently emerged as a key regulator of host immunity to infections, autoimmune diseases and cancer. In this study, we investigated the role of Bhlhe40 in protective T cell responses to the intracellular bacterium Chlamydia in the female reproductive tract (FRT). Mice deficient in Bhlhe40 exhibited severe defects in their ab...

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Literature Corpus work
6ef0da93-0a87-566c-90ab-ffb27850a638
DOI
10.1101/2023.11.02.565369
Open publication

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BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against <i>Chlamydia</i>DOI 10.1101/2023.11.02.565369
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