Article

Repairing the Epigenetics of Unstable Repeats by Genome Engineering

2021-03-10

Abstract excerpt

Epimutations are the cause of a considerable number of genetically inherited conditions in humans. All result from the mis-expression of genes due to epigenetic changes that are triggered by an underlying heritable mutation. The correction of these epigenetic defects in the context of epigenetically regulated diseases constitutes a good paradigm to probe the fundamental mechanisms underlying the development of the...

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Literature Corpus work: 6ee5610f-9a1e-5ccc-a443-23b8659602c4
DOI: 10.20944/preprints202103.0291.v1

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