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Article

Epigenetic changes and non-coding expanded repeats.

Neurobiology of disease - 1 Jul 2010

Nakamori Masayuki, Thornton Charles

Abstract excerpt

Many neurogenetic disorders are caused by unstable expansions of tandem repeats. Some of the causal mutations are located in non-protein-coding regions of genes. When pathologically expanded, these repeats can trigger focal epigenetic changes that repress the expression of the mutant allele. When...

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Identifiers

PMID: 20171282
DOI: 10.1016/j.nbd.2010.02.004
PMCID: PMC2874091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20171282-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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