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Article

Dormant spores sense amino acids through the B subunits of their germination receptors.

Nature communications - 25 Nov 2021

Artzi Lior, Alon Assaf, Brock Kelly P, Green Anna G, Tam Amy, Ramírez-Guadiana Fernando H, Marks Debora, Kruse Andrew, Rudner David Z

Abstract excerpt

Bacteria from the orders Bacillales and Clostridiales differentiate into stress-resistant spores that can remain dormant for years, yet rapidly germinate upon nutrient sensing. How spores monitor nutrients is poorly understood but in most cases requires putative membrane receptors. The prototypical receptor from Bacillus subtilis consists of three proteins (GerAA, GerAB, GerAC) required for germination in...

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Identifiers

PMID: 34824238
DOI: 10.1038/s41467-021-27235-2
PMCID: PMC8617281

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