Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Impact of YabG Mutations on Clostridioides difficile Spore Germination and Processing of Spore Substrates.

Molecular microbiology - 1 Oct 2024

Osborne Morgan S, Brehm Joshua N, Olivença Carmen, Cochran Alicia M, Serrano Mónica, Henriques Adriano O, Sorg Joseph A

Abstract excerpt

YabG is a sporulation-specific protease that is conserved among sporulating bacteria. Clostridioides difficile YabG processes the cortex destined proteins preproSleC into proSleC and CspBA to CspB and CspA. YabG also affects synthesis of spore coat/exosporium proteins CotA and CdeM. In prior work that identified CspA as the co-germinant receptor, mutations in yabG were found which altered the co-germinants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clostridioides difficile

Share to Mutation

Share to Peptide Hydrolases

Share to Spores, Bacterial

Source

Identifiers

PMID: 39258427
DOI: 10.1111/mmi.15316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Impact of YabG Mutations on Clostridioides difficile Spore Germination and Processing of Spore Substrates.PMID 39258427Read ↗

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficileSemantic proximity Read ↗

Revisiting the Role of Csp Family Proteins in Regulating Clostridium difficile Spore GerminationSemantic proximity Read ↗

Regulation of Clostridium difficile spore germination by the CspA pseudoprotease domain.Semantic proximity Read ↗

The requirement for co-germinants during Clostridium difficile spore germination is influenced by mutations in yabG and cspASemantic proximity Read ↗

The requirement for the amino acid co-germinant during <i>C. difficile</i> spore germination is influenced by mutations in <i>yabG</i> and <i>cspA</i>Semantic proximity Read ↗

A Clostridium difficile -Specific, Gel-Forming Protein Required for Optimal Spore GerminationSemantic proximity Read ↗

Functional analysis of SleC from Clostridium difficile: an essential lytic transglycosylase involved in spore germinationSemantic proximity Read ↗

SpoIIID ‐mediated regulation of σ K function during C lostridium difficile sporulationSemantic proximity Read ↗

A cortex-specific penicillin-binding protein contributes to heat resistance in Clostridioides difficile sporesSemantic proximity Read ↗

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.Semantic proximity Read ↗

Differential requirements for conserved peptidoglycan remodeling enzymes during Clostridioides difficile spore formationSemantic proximity Read ↗

Sporulation and Germination in Clostridial PathogensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.