Article

Guiding the Refinement of Biochemical Knowledgebases with Ensembles of Metabolic Networks and Machine Learning

2018-11-07

Abstract excerpt

Mechanistic models are becoming common in biology and medicine. These models are often more generalizable than data-driven models because they explicitly represent biological knowledge, enabling simulation of scenarios that were not used to construct the model. While this generalizability has advantages, it also creates a dilemma: how should model curation efforts be focused to improve model performance? Here, we...

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Literature Corpus work: 6ec00f25-3578-54d6-9d39-0f5a4981f3e9
DOI: 10.1101/460071

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