Article
High-throughput generation, optimization and analysis of genome-scale metabolic models.
Nature biotechnology - 1 Sept 2010
Henry Christopher S, DeJongh Matthew, Best Aaron A, Frybarger Paul M, Linsay Ben, Stevens Rick L
Abstract excerpt
Genome-scale metabolic models have proven to be valuable for predicting organism phenotypes from genotypes. Yet efforts to develop new models are failing to keep pace with genome sequencing. To address this problem, we introduce the Model SEED, a web-based resource for high-throughput generation, optimization and analysis of genome-scale metabolic models. The Model SEED integrates existing methods and introduces...
Topics
- Bacteria
- Genes, Bacterial
- Genome, Bacterial
- Models, Biological
- Phenotype