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Article

Therapeutic targeting of coronavirus spike glycoprotein priming

2020-04-09

Abstract excerpt

<title>Abstract</title> <p> Processing of certain viral proteins and bacterial toxins by host serine proteases is a frequent and critical step in virulence. The coronavirus spike glycoprotein contains three (S1, S2, and S2’) cleavage sites that are processed by human host proteases. The exact nature of these cleavage sites, and their respective processing proteases, can determine whether the virus can cross spec...

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Identifiers and source

Literature Corpus work
6e7d46cc-8cec-57f2-8243-d1c650f255e1
DOI
10.21203/rs.3.rs-22208/v1
Open publication

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