Article

Divergent Clinical Phenotypes, Organ Involvement, and Survival in AL Amyloidosis and Light Chain Deposition Disease: Insights From a Large Single-Center Cohort

2026-03-25

Abstract excerpt

<title>Abstract</title> <p> This retrospective single-center cohort included 480 immunoglobulin light-chain amyloidosis (AL) and 61 light chain deposition disease (LCDD) patients from Peking University First Hospital to compare clinical profiles and outcomes. AL frequently presented with multisystem (≥ 3 organs, 31.0%) and cardiac involvement (60.8%). LCDD was kidney-dominant (eGFR < 50 mL/min/1.73m², 85.2%) wit...

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Literature Corpus work: 6e55fdd6-4615-5663-a42f-de89011322cd
DOI: 10.21203/rs.3.rs-8418175/v1

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