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The evolving spectrum of kidney amyloidosis: advances in diagnosis, typing and treatment

25 Feb 2025

Abstract excerpt

Kidney amyloidosis encompasses a spectrum of heterogeneous conditions in which damage is caused by the deposition of various misfolded proteins that aggregate into fibrils. The main form of renal amyloidosis in Western countries is immunoglobulin light chain (AL) amyloidosis, which is usually secondary to a plasma cell clone or less frequently a B-cell clone, while rarer causes include AA amyloidosis, ALECT2 and...

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PMID: 40036358
DOI: 10.1093/ndt/gfaf042

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