Homology modeling of milk enzymes using on-line resources: Insights to structure-function and evolutionary relationships

Abstract excerpt

Only 1251 three-dimensional structures for bovine proteins are currently in the protein data bank (PDB), compared with over 60,000 protein sequences, demonstrating a large gap between knowledge of sequences and three-dimensional structures. An alternative approach to obtaining protein structures experimentally is to use homology modelling. In this paper, online homology modelling with Geno3D was used to create str...

Topics

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• Cattle
• Mutation
• Peptidase Inhibition and Analysis
• Protease and Inhibitor Mechanisms
• Protein Conformation
• Rats
• Sequence Homology, Nucleic Acid
• Trypsin

Identifiers and source

Literature Corpus work

6e206599-45ed-5459-9801-f18d973fdcc1

DOI

10.1016/j.idairyj.2005.09.016