Article

Novel computational deep learning strategy for neuroprotection identification reveals unique set of nicotine analogs as potential therapeutic compounds against Parkinson’s disease

2019-08-19

Abstract excerpt

Dopaminergic replacement has been used for Parkinson’s Disease (PD) treatment with positive effects on motor symptomatology but with low effects over disease progression and prevention. Different epidemiological studies have shown that nicotine consumption decreases PD prevalence through the activation of neuroprotective mechanisms. Nicotine-induced neuroprotection has been associated with the overstimulation of i...

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Literature Corpus work: 6de7a155-bdab-5cb9-9fd0-6b9e5abfdb4a
DOI: 10.1101/740050

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