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Topological Characterization of Parkinson’s Disease Drugs: A Graph-Theoretical Pilot Study

2026-03-12

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder with limited disease-modifying therapies. Computational models can provide predictive insights into drug properties, although critically limited datasets pose challenges. Fifteen FDA-approved Parkinson’s disease drugs were represented as hydrogen-suppressed molecular graphs. Twelve degree-based topological indices were computed and used as descriptors for pr...

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Literature Corpus work
36eb73c5-3dd3-57cb-8cb5-f2d55e06f77d
DOI
10.20944/preprints202603.0785.v1
Open publication

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Topological Characterization of Parkinson’s Disease Drugs: A Graph-Theoretical Pilot StudyDOI 10.20944/preprints202603.0785.v1
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