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Computational Systems Analysis of Dopamine Metabolism

17 Jun 2008

Abstract excerpt

A prominent feature of Parkinson's disease (PD) is the loss of dopamine in the striatum, and many therapeutic interventions for the disease are aimed at restoring dopamine signaling. Dopamine signaling includes the synthesis, storage, release, and recycling of dopamine in the presynaptic terminal and activation of pre- and post-synaptic receptors and various downstream signaling cascades. As an aid that might...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18568086
DOI: 10.1371/journal.pone.0002444

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