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Engineering Adenoviral Vectors With Improved GBM Selectivity

2023-04-03

Abstract excerpt

Glioblastoma (GBM) is the most common and aggressive adult brain cancer with an average survival rate of around 15 months in patients receiving standard treatment. Oncolytic adenovirus expressing therapeutic transgenes represent a promising alternative treatment for GBM. Of the many human adenoviral serotypes described to date, adenovirus 5 (Ad5) has been most utilized clinically and experimentally. However, the u...

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Literature Corpus work
6de4ef59-343a-52d7-82ee-98cf3ddc057a
DOI
10.20944/preprints202304.0027.v1
Open publication

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Engineering Adenoviral Vectors With Improved GBM SelectivityDOI 10.20944/preprints202304.0027.v1
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