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Multifactorial Chromosomal Variants Regulate Polymyxin Resistance in Extensively Drug-Resistant <i>Klebsiella pneumoniae</i>

2017-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Extensively drug-resistant Klebsiella pneumoniae (XDR-KP) infections cause high mortality and are disseminating globally. Identifying the genetic basis underpinning resistance allows for rapid diagnosis and treatment. XDR isolates sourced from Greece and Brazil, including nineteen polymyxin-resistant and five polymyxin-susceptible strains, underwent whole genome sequencing. Approximately 90% of...

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Literature Corpus work
6da2dce3-3324-5736-bd9b-e7e750e82bfc
DOI
10.1101/134684
Open publication

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