Article

RNA-Seq Reveals Allele-Specific Expression of Somatic Mutations in Neuroblastoma

2020-12-14

Abstract excerpt

Neuroblastoma (NB) is one of the most common solid tumors in children, accounting for approximately 8% of all pediatric malignancies and 15% of childhood cancer deaths. Somatic mutations in several genes such as ALK have been associated with neuroblastoma progression and can facilitate the discovery of novel therapeutic strategies. However, differential expression of mutated and wild-type alleles on the transcript...

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Literature Corpus work: 6d8894b8-af7b-5103-b2fb-d64e310db3f3
DOI: 10.21203/rs.3.rs-119906/v1

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