Article

The Impact of Cognitive Reserve on Cognitive Impairment, Brain Network Pathology and Disease Trajectory in Major Depressive Disorder

2022-09-19

Abstract excerpt

<p>Background: Cognitive reserve (CR) describes the brain's ability to buffer negative effects of disease-related structural brain alterations on cognitive functioning. Here, we analyze CR in major depressive disorder (MDD) by determining its effects on cognitive impairment, its ability to moderate the association between brain network pathology and cognitive performance, and its utility in predicting future disea...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6d81e898-82e1-55f4-bcff-404a0ee4a66c
DOI: 10.31234/osf.io/mxbku

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Impact of Cognitive Reserve on Cognitive Impairment, Brain Network Pathology and Disease Trajectory in Major Depressive DisorderDOI 10.31234/osf.io/mxbkuRead

Cognitive functioning and lifetime Major Depressive Disorder in UK BiobankSemantic proximity Read

Neurocognitive deficits, psychotrauma, and inflammation shape major depressive disorder and its phenome featuresSemantic proximity Read

Neurocognitive deficits, psychotrauma, and inflammation shape major depressive disorder and its phenome features.Semantic proximity Read

White Matter Stratification in Depression Predicts Multidimensional Antidepressant ResponsesSemantic proximity Read

Neuroanatomical dimensions in major depression: external validation and links with cognition, adverse life events, self-harm, metabolomics and geneticsSemantic proximity Read

Classification accuracy of structural and functional connectomes across different depressive phenotypesSemantic proximity Read

Multi-scale neural signatures of major depressive, anxiety, and stress-related disordersSemantic proximity Read

Age-dependent acceleration of structural brain aging in medication-free major depressive disorder linked to neuroanatomical phenotype findings from COORDINATE-MDD consortiumSemantic proximity Read

Separating Clinical and Subclinical Depression by Big Data Informed Structural Vulnerability Index and Its impact on Cognition: ENIGMA Dot ProductSemantic proximity Read

Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depressionSemantic proximity Read

Parsing clinical and neurobiological sources of heterogeneity in depressionSemantic proximity Read

Biotypes of deeply phenotyped depressed patients reflect signatures of adverse childhood experience and depressive cognitive biasesSemantic proximity Read