Article
A Novel Human Distal Tubuloid-on-a-Chip Model for Investigating Sodium and Water Transport Mechanisms
2025-03-28
Abstract excerpt
The distal segments of the nephron play a central role in regulating water and electrolyte balance, making them critical targets for therapeutic interventions. Damage to these segments is associated with significant health consequences. Studying their (patho)physiology in vivo remains challenging due to the kidney’s complex architecture. Recent advances led to the development of more representative in vitro model...
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Identifiers and source
- Literature Corpus work
- 6d7f19c1-5797-5488-b66c-413735a42ca2
- DOI
- 10.1101/2025.03.27.644139
