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Article

A Novel Human Distal Tubuloid-on-a-Chip Model for Investigating Sodium and Water Transport Mechanisms

2025-03-28

Abstract excerpt

The distal segments of the nephron play a central role in regulating water and electrolyte balance, making them critical targets for therapeutic interventions. Damage to these segments is associated with significant health consequences. Studying their (patho)physiology in vivo remains challenging due to the kidney’s complex architecture. Recent advances led to the development of more representative in vitro model...

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Literature Corpus work
6d7f19c1-5797-5488-b66c-413735a42ca2
DOI
10.1101/2025.03.27.644139
Open publication

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A Novel Human Distal Tubuloid-on-a-Chip Model for Investigating Sodium and Water Transport MechanismsDOI 10.1101/2025.03.27.644139
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