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Article

3D vascularised proximal tubules-on-a-multiplexed chip model for enhanced cell phenotypes.

Lab on a chip - 12 Jul 2023

Carracedo Miguel, Robinson Sanlin, Alaei Babak, Clausen Maryam, Hicks Ryan, Belfield Graham, Althage Magnus, Bak Annette, Lewis Jennifer A, Hansen Pernille B L, Williams Julie M

Abstract excerpt

Modelling proximal tubule physiology and pharmacology is essential to understand tubular biology and guide drug discovery. To date, multiple models have been developed; however, their relevance to human disease has yet to be evaluated. Here, we report a 3D vascularized proximal tubule-on-a-multiplexed chip (3DvasPT-MC) device composed of co-localized cylindrical conduits lined with confluent epithelium and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37341452
DOI: 10.1039/d2lc00723a
PMCID: PMC10337267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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