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Perfusable 3D models of ureteric bud and collecting duct tubules

2025-06-24

Abstract excerpt

Recent protocols have emerged to derive ureteric bud (UB) and collecting duct (CD) organoids directly from human induced pluripotent stem cells (hiPSCs). However, these 3D kidney tissues lack biophysical cues from luminal flow and a drainage outlet. To address these limitations, we have created perfusable 3D models of UB and CD tubules. UB organoids are first generated from hiPSCs followed by their dissociation in...

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Literature Corpus work
1cbe7e60-3852-50f3-9af5-6bef1e550eae
DOI
10.1101/2025.06.19.659798
Open publication

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Perfusable 3D models of ureteric bud and collecting duct tubulesDOI 10.1101/2025.06.19.659798
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