Article

The role of T-helper 17 and T-helper 22 lymphocytes in beta-lactam hypersensitivity

2016-01-01

Abstract excerpt

Beta-lactam antibiotics are used to treat recurrent opportunistic infections that occur in patients with cystic fibrosis. However, the incidence of reported hypersensitivity in these patients is greatly higher than the healthy population. Due to the delayed nature of beta-lactam hypersensitivity, a T-cell mediated immune response is implicated. Type IV drug hypersensitivity is a major clinical concern, with a cuta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6d72a681-970d-5b1d-b68d-3d36bbec0587
DOI: 10.17638/03004574

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of T-helper 17 and T-helper 22 lymphocytes in beta-lactam hypersensitivityDOI 10.17638/03004574Read

Characterisation of the B-lymphocyte response in delayed-type piperacillin hypersensitivity reactionsSemantic proximity Read

Characterisation of drug-specific T-cell responses in hypersensitive patients and healthy donorsSemantic proximity Read

The phenotype and function of hapten specific T-Cell isolated from hypersensitive patients and healthy human donorsSemantic proximity Read

Helper T cell subsets: Development, function and clinical role in hypersensitivity reactions in the modern perspectiveSemantic proximity Read

Phenotypic diversity in delayed drug hypersensitivity: an immunologic explanation.Semantic proximity Read

Development and use of a mouse model to investigate β-lactam hypersensitivity reactionsSemantic proximity Read

T-cell Subsets and Antifungal Host DefensesSemantic proximity Read

Elucidating CD4+ and CD8+ T-cell involvement in patients with vancomycin-induced DRESS.Semantic proximity Read

Prediction of hypersensitivity to antibiotics: what factors need to be considered?Semantic proximity Read

Type 1 T helper and type 2 T helper cells: functions, regulation and role in protection and disease.Semantic proximity Read

Generation and characterization of dapsone- and nitroso-dapsone-specific T-cells : an insight into the molecular pathomechanism of dapsone hypersensitivity syndromeSemantic proximity Read

PATTERNS OF RESPONSE AND DRUGS INVOLVED IN HYPERSENSITIVITY REACTIONS TO BETA-LACTAMS IN CHILDREN.Semantic proximity Read